A Bim-activating mould
نویسندگان
چکیده
منابع مشابه
ER Stress Triggers Apoptosis by Activating BH3-Only Protein Bim
Endoplasmic reticulum (ER) stress caused by misfolded proteins or cytotoxic drugs can kill cells and although activation of this pathway has been implicated in the etiology of certain degenerative disorders its mechanism remains unresolved. Bim, a proapoptotic BH3-only member of the Bcl-2 family is required for initiation of apoptosis induced by cytokine deprivation or certain stress stimuli. I...
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ژورنال
عنوان ژورنال: Cell Death & Differentiation
سال: 2013
ISSN: 1350-9047,1476-5403
DOI: 10.1038/cdd.2013.98